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Lee YJ, Shin KJ, Chae YC (2024) Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer

During high levels of release, serotonin spills over to reach extra-synaptic receptor sites in the initial axon segment of motoneurons, inhibiting action potential generation (Cotel et al

One of the most promising adoptive cell transfer approaches is chimeric antigen receptor (CAR) T-cell therapy, where T cells are genetically engineered to express a synthetic receptor that recognizes specific tumor-associated antigens

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Activation of MC4R in particular is associated with reduced appetite and potential weight loss

These modifications reduce affinity for IGF-binding proteins